bs-6597R-Cy7 [Conjugated Primary Antibody]
Podocin Polyclonal Antibody, Cy7 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Podocin

Immunogen Range: 231-330/383


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7827

Swiss Prot: Q9NP85

Source: KLH conjugated synthetic peptide derived from human Podocin

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.

Conjugation: Cy7

Excitation/ Emission: 743nm/767nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 42


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Cow
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhang, Xiao-Liang, et al. "Vitamin D Prevents Podocyte Injury Via Regulation Of Macrophage M1/M2 Phenotype In Diabetic Nephropathy Rats." Endocrinology (2014).Read more>>
  • Jayachandran, Muthuvel, et al. "Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study." Biol Sex Differ 6.2 (2015).Read more>>
  • Garovic, Vesna D., and Muthuvel Jayachandran. "DETECTING PODOCYTE INJURY IN DIABETIC NEPHROPATHY AND GLOMERULONEPHRITIS." U.S. Patent No. 20,170,003,299. 5 Jan. 2017.Read more>>
  • Ishida et al. Kidney-specific Sonoporation-mediated Gene Transfer. (2016) Mol.The. 24:125-34Read more>>
  • Turco et al. Specific renal parenchymal-derived urinary extracellular vesicles identify age-associated structural changes in living donor kidneys. (2016) J.Extracell.Vesicle. 5:29642Read more>>
  • Maeda et al. CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease. (2018) J.Clin.Invest. 128:3445-3459Read more>>
  • Maeda et al. CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease. (2018) J.Clin.Invest. 128:3445-3459Read more>>
  • Cao S et al. Effect of shenyan xiaobai granule on nephrin and podocin of adriamycin-induced renal injury: A randomised controlled trial. J Ethnopharmacol. 2019 Nov 15;244:112104. Read more>>
  • Fang-Hao Cai. et al. Diagnostic roles of urinary kidney microvesicles in diabetic nephropathy. Ann Transl Med. 2020 Nov; 8(21): 1431Read more>>
  • Alberto Mella. et al. Detection of urinary podocytes by flow cytometry in idiopathic membranous nephropathy. Sci Rep-Uk. 2020 Oct;10(1):1-7Read more>>
  • Nan Zang. et al. cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease. ISCIENCE. 2022 Sep;:105145Read more>>
  • Mohani Chandra Irwanadi. et al. DLBS3233 enhances nephrin and podocin expression also reduces oxidative stress marker and insulin receptor serine diabetic rats podocytes. ANN MED SURG. 2023 Mar;:10.1097/MS9.0000000000000308Read more>>
  • Shin Young Kim. et al. Characterizing Glomerular Barrier Dysfunction with Patient-Derived Serum in Glomerulus-on-a-Chip Models: Unveiling New Insights into Glomerulonephritis. INT J MOL SCI. 2024 Jan;25(10):5121Read more>>
  • J.I. Yue. et al. Acupuncture improve proteinuria in diabetic kidney disease rats by inhibiting ferroptosis and epithelial-mesenchymal transition. HELIYON. 2024 Jul;1Read more>>
VALIDATION IMAGES