bs-6559C [Life Science]
SB216763
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Formulation Powder

Storage: Store in dry, dark place at -20C for 1 year.

Product Information:

Molecular Weight: 371.22

Formula: C19 H12 Cl2 N2 O2

CAS Number: 280744-09-4

InChi Key: JCSGFHVFHSKIJH-UHFFFAOYSA-N

InChi: InChI=1S/C19H12Cl2N2O2/c1-23-9-13(11-4-2-3-5-15(11)23)17-16(18(24)22-19(17)25)12-7-6-10(20)8-14(12)21/h2-9H,1H3,(H,22,24,25)

Smiles: CN1C=C(C2=C(C3C=CC(Cl)=CC=3Cl)C(=O)NC2=O)C2=CC=CC=C12

Purity: 98.0

Solubility: Soluble in DMSO, not in water

Appearance: Solid Power

Shelf Life: 1.0 years

Description:

SB-216763 is a glycogen synthase kinase-3 (GSK3) inhibitor, which can maintain mouse embryonic stem cells (mESCs) in a pluripotent state in the absence of exogenous leukemia inhibitory factor (LIF) when cultured on mouse embryonic fibroblasts (MEFs). SB-216763 is the first GSK3 inhibitor that can promote self-renewal of mESC co-cultured with MEFs for more than two months.

Size: 10mg solid, 2mg solid 10mg solid, 2mg solid

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.