bs-6549C
[Life Science]
BLU-554
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 503.38
Formula: C24 H24 Cl2 N4 O4
CAS Number: 1707289-21-1
InChi Key: MGZKYOAQVGSSGC-DLBZAZTESA-N
InChi: InChI=1S/C24H24Cl2N4O4/c1-4-20(31)28-16-7-8-34-12-17(16)30-24-27-11-14-9-13(5-6-15(14)29-24)21-22(25)18(32-2)10-19(33-3)23(21)26/h4-6,9-11,16-17H,1,7-8,12H2,2-3H3,(H,28,31)(H,27,29,30)/t16-,17+/m0/s1
Smiles: COC1C=C(OC)C(Cl)=C(C2C=C3C=NC(N[C@@H]4COCC[C@@H]4NC(=O)C=C)=NC3=CC=2)C=1Cl
Purity: 98.0
Solubility: DMSO: 100 mg/mLwarmed(198.65 mM).
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C24 H24 Cl2 N4 O4
CAS Number: 1707289-21-1
InChi Key: MGZKYOAQVGSSGC-DLBZAZTESA-N
InChi: InChI=1S/C24H24Cl2N4O4/c1-4-20(31)28-16-7-8-34-12-17(16)30-24-27-11-14-9-13(5-6-15(14)29-24)21-22(25)18(32-2)10-19(33-3)23(21)26/h4-6,9-11,16-17H,1,7-8,12H2,2-3H3,(H,28,31)(H,27,29,30)/t16-,17+/m0/s1
Smiles: COC1C=C(OC)C(Cl)=C(C2C=C3C=NC(N[C@@H]4COCC[C@@H]4NC(=O)C=C)=NC3=CC=2)C=1Cl
Purity: 98.0
Solubility: DMSO: 100 mg/mLwarmed(198.65 mM).
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
BLU-554, also known as Fisogatinib, is a fibroblast growth factor receptor 4 (FGFR4) inhibitor potentially for the treatment of hepatocellular carcinoma and cholangiocarcinoma. BLU-554 demonstrates clinical benefit and tumor regression in patients with HCC with aberrant FGF19 expression.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.