DATASHEET
Formulation
Powder
Storage:
Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 427.42
Formula: C21 H15 F2 N3 O3 S
CAS Number: 1362154-70-8
InChi Key: XRDVXQQZLHVEQZ-UHFFFAOYSA-N
InChi: InChI=1S/C21H15F2N3O3S/c22-16-9-17(23)11-19(10-16)30(28,29)18-4-1-14(2-5-18)12-25-21(27)15-3-6-20-24-7-8-26(20)13-15/h1-11,13H,12H2,(H,25,27)
Smiles: O=C(NCC1C=CC(=CC=1)S(=O)(=O)C1C=C(F)C=C(F)C=1)C1=CN2C=CN=C2C=C1
Purity: 98.0
Solubility: DMSO: 42 mg/mL(98.26 mM).
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
GNE-617 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with IC50 value of 5nM. Prolonged inhibition of nicotinamide phosphoribosyltransferase (NAMPT) is a strategy for targeting cancer metabolism.