DATASHEET
Formulation
Powder
Storage:
Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 396.44
Formula: C20 H24 N6 O3
CAS Number: 192705-79-6
InChi Key: NHJSWORVNIOXIT-UHFFFAOYSA-N
InChi: InChI=1S/C20H24N6O3/c1-20(2,3)26-19(27)25-17-15(8-12-10-22-18(21)24-16(12)23-17)11-6-13(28-4)9-14(7-11)29-5/h6-10H,1-5H3,(H4,21,22,23,24,25,26,27)
Smiles: CC(C)(C)NC(=O)NC1N=C2N=C(N)N=CC2=CC=1C1C=C(C=C(C=1)OC)OC
Purity: 98.0
Solubility: DMSO: 14 mg/mLwarmed(35.31 mM).
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
PD-166866 is a selective inhibitor of the FGF-1 receptor tyrosine kinase (FGFR1) with IC50 = 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4. PD-166866 has clear antiproliferative effects.