bs-6540C
[Life Science]
BGJ-398
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 560.48
Formula: C26 H31 Cl2 N7 O3
CAS Number: 872511-34-7
InChi Key: QADPYRIHXKWUSV-UHFFFAOYSA-N
InChi: InChI=1S/C26H31Cl2N7O3/c1-5-34-10-12-35(13-11-34)18-8-6-17(7-9-18)31-21-15-22(30-16-29-21)33(2)26(36)32-25-23(27)19(37-3)14-20(38-4)24(25)28/h6-9,14-16H,5,10-13H2,1-4H3,(H,32,36)(H,29,30,31)
Smiles: CN(C(=O)NC1C(Cl)=C(C=C(OC)C=1Cl)OC)C1C=C(NC2C=CC(=CC=2)N2CCN(CC2)CC)N=CN=1
Purity: 98.0
Solubility: DMSO: 1 mg/mLwarmed(1.78 mM).
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C26 H31 Cl2 N7 O3
CAS Number: 872511-34-7
InChi Key: QADPYRIHXKWUSV-UHFFFAOYSA-N
InChi: InChI=1S/C26H31Cl2N7O3/c1-5-34-10-12-35(13-11-34)18-8-6-17(7-9-18)31-21-15-22(30-16-29-21)33(2)26(36)32-25-23(27)19(37-3)14-20(38-4)24(25)28/h6-9,14-16H,5,10-13H2,1-4H3,(H,32,36)(H,29,30,31)
Smiles: CN(C(=O)NC1C(Cl)=C(C=C(OC)C=1Cl)OC)C1C=C(NC2C=CC(=CC=2)N2CCN(CC2)CC)N=CN=1
Purity: 98.0
Solubility: DMSO: 1 mg/mLwarmed(1.78 mM).
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
BGJ-398, also known as, Infigratinib or NVP-BGJ398, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. pan FGFR kinase inhibitor BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.