bs-6537C
[Life Science]
Eg5 Inhibitor III
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 302.39
Formula: C16 H18 N2 O2 S
CAS Number: 863774-58-7
InChi Key: RUOOPLOUUAYNPY-UHFFFAOYSA-N
InChi: InChI=1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6,14,19H,7-8H2,1-2H3,(H2,17,18,21)
Smiles: CC1(C)CC2NC(=S)NC(C=2C(=O)C1)C1C=CC=C(O)C=1
Purity: 98.0
Solubility: DMSO : 100 mg/mL (330.70 mM; Need ultrasonic)
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C16 H18 N2 O2 S
CAS Number: 863774-58-7
InChi Key: RUOOPLOUUAYNPY-UHFFFAOYSA-N
InChi: InChI=1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6,14,19H,7-8H2,1-2H3,(H2,17,18,21)
Smiles: CC1(C)CC2NC(=S)NC(C=2C(=O)C1)C1C=CC=C(O)C=1
Purity: 98.0
Solubility: DMSO : 100 mg/mL (330.70 mM; Need ultrasonic)
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
Eg5 Inhibitor III is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Eg5 Inhibitor III suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5. The inhibition of kinesin Eg5 by small molecules such as monastrol is currently evaluated as an approach to develop a novel class of antiproliferative drugs for the treatment of malignant tumours.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.