bs-6526C
[Life Science]
VU-0357121
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 305.32
Formula: C17 H17 F2 N O2
CAS Number: 433967-28-3
InChi Key: AHCYOTLTLQTPSU-UHFFFAOYSA-N
InChi: InChI=1S/C17H17F2NO2/c1-2-3-10-22-14-7-4-12(5-8-14)17(21)20-16-9-6-13(18)11-15(16)19/h4-9,11H,2-3,10H2,1H3,(H,20,21)
Smiles: CCCCOC1C=CC(=CC=1)C(=O)NC1C=CC(F)=CC=1F
Purity: 98.0
Solubility: DMSO: 61 mg/mL(199.79 mM).
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C17 H17 F2 N O2
CAS Number: 433967-28-3
InChi Key: AHCYOTLTLQTPSU-UHFFFAOYSA-N
InChi: InChI=1S/C17H17F2NO2/c1-2-3-10-22-14-7-4-12(5-8-14)17(21)20-16-9-6-13(18)11-15(16)19/h4-9,11H,2-3,10H2,1H3,(H,20,21)
Smiles: CCCCOC1C=CC(=CC=1)C(=O)NC1C=CC(F)=CC=1F
Purity: 98.0
Solubility: DMSO: 61 mg/mL(199.79 mM).
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
VU-0357121 is a positive allosteric modulator of mGlu5 receptors (EC50 = 33 nM). Mutagenesis studies indicate that VU-0357121 and related analogues bind to a yet uncharacterized allosteric site on mGlu(5), distinct from CPPHA, yet share a functional interaction with the MPEP site.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.