bs-6522C
[Life Science]
TUG-891
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 364.41
Formula: C23 H21 F O3
CAS Number: 1374516-07-0
InChi Key: LPGBXHWIQNZEJB-UHFFFAOYSA-N
InChi: InChI=1S/C23H21FO3/c1-16-2-7-18(8-3-16)22-12-9-20(24)14-19(22)15-27-21-10-4-17(5-11-21)6-13-23(25)26/h2-5,7-12,14H,6,13,15H2,1H3,(H,25,26)
Smiles: CC1C=CC(=CC=1)C1C=CC(F)=CC=1COC1C=CC(CCC(O)=O)=CC=1
Purity: 98.0
Solubility: DMSO : ≥ 180 mg/mL (493.95 mM)
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C23 H21 F O3
CAS Number: 1374516-07-0
InChi Key: LPGBXHWIQNZEJB-UHFFFAOYSA-N
InChi: InChI=1S/C23H21FO3/c1-16-2-7-18(8-3-16)22-12-9-20(24)14-19(22)15-27-21-10-4-17(5-11-21)6-13-23(25)26/h2-5,7-12,14H,6,13,15H2,1H3,(H,25,26)
Smiles: CC1C=CC(=CC=1)C1C=CC(F)=CC=1COC1C=CC(CCC(O)=O)=CC=1
Purity: 98.0
Solubility: DMSO : ≥ 180 mg/mL (493.95 mM)
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
TUG-891 is a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), which demonstrates both potential opportunity and possible challenges to therapeutic agonism. Activation of human FFA4 by TUG-891 also resulted in rapid phosphorylation and internalization of the receptor. TUG-891 was also a potent agonist of mouse FFA4, but it showed only limited selectivity over mouse FFA1, complicating its use in vivo in this species.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.