bs-6521C
[Life Science]
TRX-818
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 393.21
Formula: C16 H11 F N Na2 O5 P
CAS Number: 1256037-58-7
InChi Key: ZRPWVAHVWBPHID-UHFFFAOYSA-L
InChi: InChI=1S/C16H13FNO5P.2Na/c1-23-14-6-5-11-15(16(14)24(20,21)22)13(19)8-12(18-11)9-3-2-4-10(17)7-9;;/h2-8H,1H3,(H,18,19)(H2,20,21,22);;/q;2*+1/p-2
Smiles: [Na+].[Na+].COC1=CC=C2NC(=CC(=O)C2=C1P([O-])([O-])=O)C1=CC(F)=CC=C1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C16 H11 F N Na2 O5 P
CAS Number: 1256037-58-7
InChi Key: ZRPWVAHVWBPHID-UHFFFAOYSA-L
InChi: InChI=1S/C16H13FNO5P.2Na/c1-23-14-6-5-11-15(16(14)24(20,21)22)13(19)8-12(18-11)9-3-2-4-10(17)7-9;;/h2-8H,1H3,(H,18,19)(H2,20,21,22);;/q;2*+1/p-2
Smiles: [Na+].[Na+].COC1=CC=C2NC(=CC(=O)C2=C1P([O-])([O-])=O)C1=CC(F)=CC=C1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
TRX-818, also known as Foslinanib, CVM-1118, is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities. Although the exact multiple mechanisms of action through which this agent exerts its effects have yet to be fully elucidated, TRX-818, upon oral administration appears to induce cancer cell apoptosis and inhibits cancer cell proliferation. This agent also prevents tumor cell VM by blocking the formation of vasculogenic-like tubular structures through an as of yet undetermined mechanism of action.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.