bs-6503C
[Life Science]
CPI-0610
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 365.81
Formula: C20 H16 Cl N3 O2
CAS Number: 1380087-89-7
InChi Key: GCWIQUVXWZWCLE-INIZCTEOSA-N
InChi: InChI=1S/C20H16ClN3O2/c1-11-18-14-4-2-3-5-15(14)19(12-6-8-13(21)9-7-12)23-16(10-17(22)25)20(18)26-24-11/h2-9,16H,10H2,1H3,(H2,22,25)/t16-/m0/s1
Smiles: CC1=NOC2[C@H](CC(N)=O)N=C(C3C=CC=CC=3C=21)C1C=CC(Cl)=CC=1
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C20 H16 Cl N3 O2
CAS Number: 1380087-89-7
InChi Key: GCWIQUVXWZWCLE-INIZCTEOSA-N
InChi: InChI=1S/C20H16ClN3O2/c1-11-18-14-4-2-3-5-15(14)19(12-6-8-13(21)9-7-12)23-16(10-17(22)25)20(18)26-24-11/h2-9,16H,10H2,1H3,(H2,22,25)/t16-/m0/s1
Smiles: CC1=NOC2[C@H](CC(N)=O)N=C(C3C=CC=CC=3C=21)C1C=CC(Cl)=CC=1
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
CPI-0610, also known as Pelabresib, is a small molecule inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with potential antineoplastic activity. Upon administration, the BET inhibitor CPI-0610 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histone peptides. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to an inhibition of tumor cell growth.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.