bs-6502C
[Life Science]
BPTES
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 524.68
Formula: C24 H24 N6 O2 S3
CAS Number: 314045-39-1
InChi Key: MDJIPXYRSZHCFS-UHFFFAOYSA-N
InChi: InChI=1S/C24H24N6O2S3/c31-19(15-17-7-3-1-4-8-17)25-23-29-27-21(34-23)11-13-33-14-12-22-28-30-24(35-22)26-20(32)16-18-9-5-2-6-10-18/h1-10H,11-16H2,(H,25,29,31)(H,26,30,32)
Smiles: O=C(CC1=CC=CC=C1)NC1=NN=C(CCSCCC2=NN=C(NC(=O)CC3=CC=CC=C3)S2)S1
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C24 H24 N6 O2 S3
CAS Number: 314045-39-1
InChi Key: MDJIPXYRSZHCFS-UHFFFAOYSA-N
InChi: InChI=1S/C24H24N6O2S3/c31-19(15-17-7-3-1-4-8-17)25-23-29-27-21(34-23)11-13-33-14-12-22-28-30-24(35-22)26-20(32)16-18-9-5-2-6-10-18/h1-10H,11-16H2,(H,25,29,31)(H,26,30,32)
Smiles: O=C(CC1=CC=CC=C1)NC1=NN=C(CCSCCC2=NN=C(NC(=O)CC3=CC=CC=C3)S2)S1
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
BPTES is a selective inhibitor of Glutaminase GLS1 (KGA), which is found in the kidney and brain, and is positively regulated by myc and strongly expressed in many tumors and tumor cell lines. BPTES has a K(i) of approx. 3 microM. BPTES inhibits the allosteric activation caused by phosphate binding and promotes the formation of an inactive complex.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.