bs-6496C
[Life Science]
NCB-0846
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 375.42
Formula: C21 H21 N5 O2
CAS Number: 1792999-26-8
InChi Key: FYWRWBSYRGSWIQ-IYBDPMFKSA-N
InChi: InChI=1S/C21H21N5O2/c27-15-5-7-16(8-6-15)28-19-3-1-2-13-11-22-21(26-20(13)19)25-14-4-9-17-18(10-14)24-12-23-17/h1-4,9-12,15-16,27H,5-8H2,(H,23,24)(H,22,25,26)/t15-,16+
Smiles: O[C@@H]1CC[C@@H](CC1)OC1C=CC=C2C=NC(NC3C=CC4N=CNC=4C=3)=NC2=1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C21 H21 N5 O2
CAS Number: 1792999-26-8
InChi Key: FYWRWBSYRGSWIQ-IYBDPMFKSA-N
InChi: InChI=1S/C21H21N5O2/c27-15-5-7-16(8-6-15)28-19-3-1-2-13-11-22-21(26-20(13)19)25-14-4-9-17-18(10-14)24-12-23-17/h1-4,9-12,15-16,27H,5-8H2,(H,23,24)(H,22,25,26)/t15-,16+
Smiles: O[C@@H]1CC[C@@H](CC1)OC1C=CC=C2C=NC(NC3C=CC4N=CNC=4C=3)=NC2=1
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
NCB-0846 is the first orally available small-molecule TNIK inhibitor, having anti-Wnt activity and suppressing Wnt-driven intestinal tumorigenesis, also inhibiting FLT3, JAK3, PDGFRa, TRKA, CDK2/CycA2, and HGK.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.