bs-6487C
[Life Science]
AUY-922
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 465.54
Formula: C26 H31 N3 O5
CAS Number: 747412-49-3
InChi Key: NDAZATDQFDPQBD-UHFFFAOYSA-N
InChi: InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32)
Smiles: CCNC(=O)C1=NOC(=C1C1=CC=C(CN2CCOCC2)C=C1)C1C=C(C(C)C)C(O)=CC=1O
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C26 H31 N3 O5
CAS Number: 747412-49-3
InChi Key: NDAZATDQFDPQBD-UHFFFAOYSA-N
InChi: InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32)
Smiles: CCNC(=O)C1=NOC(=C1C1=CC=C(CN2CCOCC2)C=C1)C1C=C(C(C)C)C(O)=CC=1O
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
AUY-922, also known as Luminespib, NVP-AUY922, VER52296, is a derivative of 4, 5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY-922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock protein 72 (Hsp72) in a wide range of human tumor cell lines.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.