bs-6460R

DATASHEET

Host: Rabbit

Target Protein: Mycobacterium tuberculosis Ag85A/B

Specificity: This antibody will detect both Mycobacterium tuberculosis Ag85A and Mycobacterium tuberculosis Ag85B

Immunogen Range: 115-154/325

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 885785, 886132

Swiss Prot: P9WQP1, P9WQP3

Source: KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis Antigen 85 complex B

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 31

Cross Reactive Species: Bacteria
(Mycobacteriumtuberculosis)

For research use only. Not intended for diagnostic or therapeutic use.