bs-6456R-HRP [Conjugated Primary Antibody]
PEN2 Polyclonal Antibody, HRP Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: PEN2

Specificity: Belongs to the PEN-2 family

Immunogen Range: 6-80/101


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 55851

Swiss Prot: Q9NZ42

Source: KLH conjugated synthetic peptide derived from human PEN2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.

Conjugation: HRP

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 11


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Dog
Cow
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Chu, Yanan, et al. "Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice." Acta Biochimica et Biophysica Sinica (2015): gmv010.Read more>>
  • Chu et al. Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice. (2015) Acta.Biochim.Biophys.Sin.(Shanghai). 47:258-66Read more>>
VALIDATION IMAGES