bs-6453C
[Life Science]
Lorediplon
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 394.42
Formula: C20 H15 F N4 O2 S
CAS Number: 917393-39-6
InChi Key: NQPOCLFSADOXBR-UHFFFAOYSA-N
InChi: InChI=1S/C20H15FN4O2S/c1-12(26)24(2)17-10-13(5-6-15(17)21)16-7-8-22-20-14(11-23-25(16)20)19(27)18-4-3-9-28-18/h3-11H,1-2H3
Smiles: CN(C1C=C(C=CC=1F)C1=CC=NC2=C(C=NN12)C(=O)C1=CC=CS1)C(C)=O
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C20 H15 F N4 O2 S
CAS Number: 917393-39-6
InChi Key: NQPOCLFSADOXBR-UHFFFAOYSA-N
InChi: InChI=1S/C20H15FN4O2S/c1-12(26)24(2)17-10-13(5-6-15(17)21)16-7-8-22-20-14(11-23-25(16)20)19(27)18-4-3-9-28-18/h3-11H,1-2H3
Smiles: CN(C1C=C(C=CC=1F)C1=CC=NC2=C(C=NN12)C(=O)C1=CC=CS1)C(C)=O
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
Lorediplon is a nonbenzodiazepine of the pyrazolopyrimidine family that is being pursued as a treatment for insomnia but has not completed development. Lorediplon demonstrated a dose-dependent improvement in sleep, whereas zolpidem showed a more sustained WASO effect. No next-day hangover effects were observed. These sleep effects are also consistent with the pharmacokinetic profile of lorediplon. These results warrant clinical trials in patients with insomnia.
Size: 10mg solid, 2mg solid 10mg solid, 2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.