bs-6445C
[Life Science]
ABT-888 dihydrochloride
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 317.21
Formula: C13 H18 Cl2 N4 O
CAS Number: 912445-05-7
InChi Key: DSBSVDCHFMEYBX-FFXKMJQXSA-N
InChi: InChI=1S/C13H16N4O.2ClH/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12;;/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17);2*1H/t13-;;/m1../s1
Smiles: Cl.Cl.C[C@@]1(CCCN1)C1NC2C(=CC=CC=2N=1)C(N)=O
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C13 H18 Cl2 N4 O
CAS Number: 912445-05-7
InChi Key: DSBSVDCHFMEYBX-FFXKMJQXSA-N
InChi: InChI=1S/C13H16N4O.2ClH/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12;;/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17);2*1H/t13-;;/m1../s1
Smiles: Cl.Cl.C[C@@]1(CCCN1)C1NC2C(=CC=CC=2N=1)C(N)=O
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
ABT-888 dihydrochloride, also known asVeliparib, is a potent and selective Poly (ADP-Ribose) Polymerase (PARP) Inhibitor. ABT-888 dihydrochloride enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT-888 dihydrochloride is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5.2 and 2.9 nM, respectively).
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.