DATASHEET
Formulation
Powder
Storage:
Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 375.85
Formula: C20 H22 Cl N O4
CAS Number: 1308256-94-1
InChi Key: PWYAUIUPDMSWJH-UGSOOPFHSA-N
InChi: InChI=1S/C20H22ClNO4/c1-3-26-20(25)13(2)22-18(19(23)24)11-14-7-9-15(10-8-14)16-5-4-6-17(21)12-16/h4-10,12-13,18,22H,3,11H2,1-2H3,(H,23,24)/t13-,18-/m0/s1
Smiles: C[C@H](N[C@@H](CC1C=CC(=CC=1)C1=CC(Cl)=CC=C1)C(O)=O)C(=O)OCC
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
LHW090-A7 is a compound developed as an inhibitor of neutral endopeptidase (NEP), an enzyme responsible for the metabolic inactivation of enkephalins.1 Inhibitors of NEP have been shown to increase plasma levels of endogenous atrial natriuretic peptides and, as such, are expected to induce natriuretic and diuretic effects.