bs-6422C
[Life Science]
GNE-7915
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 443.4
Formula: C19 H21 F4 N5 O3
CAS Number: 1351761-44-8
InChi Key: XCFLWTZSJYBCPF-UHFFFAOYSA-N
InChi: InChI=1S/C19H21F4N5O3/c1-3-24-16-12(19(21,22)23)10-25-18(27-16)26-14-9-13(20)11(8-15(14)30-2)17(29)28-4-6-31-7-5-28/h8-10H,3-7H2,1-2H3,(H2,24,25,26,27)
Smiles: COC1=CC(C(=O)N2CCOCC2)=C(F)C=C1NC1N=C(NCC)C(=CN=1)C(F)(F)F
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C19 H21 F4 N5 O3
CAS Number: 1351761-44-8
InChi Key: XCFLWTZSJYBCPF-UHFFFAOYSA-N
InChi: InChI=1S/C19H21F4N5O3/c1-3-24-16-12(19(21,22)23)10-25-18(27-16)26-14-9-13(20)11(8-15(14)30-2)17(29)28-4-6-31-7-5-28/h8-10H,3-7H2,1-2H3,(H2,24,25,26,27)
Smiles: COC1=CC(C(=O)N2CCOCC2)=C(F)C=C1NC1N=C(NCC)C(=CN=1)C(F)(F)F
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
GNE-7915 is a potent LRRK2 kinase inhibitor, which possess an ideal balance of LRRK2 cellular potency, broad kinase selectivity, metabolic stability, and brain penetration across multiple species. GNE-7915 was reported as a potent (IC50=9 nM) selective (1/187 kinases), brain-penetrant and non-toxic inhibitor of LRRK2.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.