bs-6420C
[Life Science]
CK-1827452
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 401.43
Formula: C20 H24 F N5 O3
CAS Number: 873697-71-3
InChi Key: RFUBTTPMWSKEIW-UHFFFAOYSA-N
InChi: InChI=1S/C20H24FN5O3/c1-14-6-7-16(12-22-14)23-19(27)24-17-5-3-4-15(18(17)21)13-25-8-10-26(11-9-25)20(28)29-2/h3-7,12H,8-11,13H2,1-2H3,(H2,23,24,27)
Smiles: CC1=CC=C(C=N1)NC(=O)NC1=CC=CC(CN2CCN(CC2)C(=O)OC)=C1F
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C20 H24 F N5 O3
CAS Number: 873697-71-3
InChi Key: RFUBTTPMWSKEIW-UHFFFAOYSA-N
InChi: InChI=1S/C20H24FN5O3/c1-14-6-7-16(12-22-14)23-19(27)24-17-5-3-4-15(18(17)21)13-25-8-10-26(11-9-25)20(28)29-2/h3-7,12H,8-11,13H2,1-2H3,(H2,23,24,27)
Smiles: CC1=CC=C(C=N1)NC(=O)NC1=CC=CC(CN2CCN(CC2)C(=O)OC)=C1F
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
CK-1827452 is a cardiac specific myosin activator. It is clinically tested for its role in the treatment of left ventricular systolic heart failure. CK-1827452 specifically targets and activates myocardial ATPase and improves energy utilization. CK-1827452 improves systolic function by increasing the systolic ejection duration/stroke volume, without consuming more ATP energy, oxygen or altering intracellular calcium levels causing an overall improvement in cardiac efficiency.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.