bs-6417C
[Life Science]
BMS-201038
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 693.72
Formula: C39 H37 F6 N3 O2
CAS Number: 182431-12-5
InChi Key: MBBCVAKAJPKAKM-UHFFFAOYSA-N
InChi: InChI=1S/C39H37F6N3O2/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)26-15-17-27(18-16-26)39(43,44)45/h1-6,9-18,28H,7-8,19-25H2,(H,46,50)(H,47,49)
Smiles: O=C(NCC(F)(F)F)C1(CCCCN2CCC(CC2)NC(=O)C2=CC=CC=C2C2C=CC(=CC=2)C(F)(F)F)C2=CC=CC=C2C2C=CC=CC1=2
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C39 H37 F6 N3 O2
CAS Number: 182431-12-5
InChi Key: MBBCVAKAJPKAKM-UHFFFAOYSA-N
InChi: InChI=1S/C39H37F6N3O2/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)26-15-17-27(18-16-26)39(43,44)45/h1-6,9-18,28H,7-8,19-25H2,(H,46,50)(H,47,49)
Smiles: O=C(NCC(F)(F)F)C1(CCCCN2CCC(CC2)NC(=O)C2=CC=CC=C2C2C=CC(=CC=2)C(F)(F)F)C2=CC=CC=C2C2C=CC=CC1=2
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
BMS-201038 is a MTP inhibitor. Lomitapid is a novel agent for the treatment of homozygous familial hypercholesterolemia. Lomitapide is an orally active inhibitor of microsomal triglyceride transfer protein that is indicated as an adjunct to a low-fat diet and other lipid-lowering treatments, including LDL apheresis where available for the reduction of LDL-C, total cholesterol, apolipoprotein B, and non-high-density lipoprotein cholesterol in adult patients with HoFH.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.