DATASHEET
Formulation
Powder
Storage:
Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 416.99
Formula: C22 H33 Cl N6
CAS Number: 1397219-81-6
InChi Key: NVIJWMOQODWNFN-UHFFFAOYSA-N
InChi: InChI=1S/C22H32N6.ClH/c1-17(2)19-16-26-28-21(25-15-18-10-6-5-7-11-18)14-20(27-22(19)28)24-13-9-4-3-8-12-23;/h5-7,10-11,14,16-17,25H,3-4,8-9,12-13,15,23H2,1-2H3,(H,24,27);1H
Smiles: Cl.CC(C)C1C=NN2C(=CC(NCCCCCCN)=NC2=1)NCC1C=CC=CC=1
Purity: 98.0
Solubility: ≥ 20.85mg/mL in DMSO, ≥ 6.49 mg/mL in EtOH with ultrasonic
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
BS-181 HCl is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.