bs-6412C [Life Science]
Triapine
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Formulation Powder

Storage: Store in dry, dark place at -20C for 1 year.

Product Information:

Molecular Weight: 195.24

Formula: C7 H9 N5 S

CAS Number: 143621-35-6

InChi Key: XMYKNCNAZKMVQN-NYYWCZLTSA-N

InChi: InChI=1S/C7H9N5S/c8-5-2-1-3-10-6(5)4-11-12-7(9)13/h1-4H,8H2,(H3,9,12,13)/b11-4+

Smiles: NC1=CC=CN=C1/C=N/NC(N)=S

Purity: 98.0

Solubility: Soluble in DMSO, not in water

Appearance: Solid Power

Shelf Life: 1.0 years

Description:

Triapine, also known as 3-AP and OCX-191, is a synthetic heterocyclic carboxaldehyde thiosemicarbazone with potential antineoplastic activity. Triapine inhibits the enzyme ribonucleotide reductase, resulting in the inhibition of the conversion of ribonucleoside diphosphates to deoxyribonucleotides necessary for DNA synthesis. This agent has been shown to inhibit tumor growth in vitro.

Size: 10mg solid, 2mg solid 10mg solid, 2mg solid

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.