bs-6359R [Primary Antibody]
Glutamine PRPP amidotransferase Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Glutamine PRPP amidotransferase

Immunogen Range: 351-430/517


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5471

Swiss Prot: Q06203

Source: KLH conjugated synthetic peptide derived from human Glutamine PRPP amidotransferase

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Phosphoribosyl pyrophosphate amidotransferase (PPAT) is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. The genes for PPAT and PAICS/AIRC, (a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway), are located in close proximity on chromosome 4.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 56


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Dog
Cow
Sheep
Pig
Horse
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Pengfei Zhang. et al. Dietary intake of fructose increases purine de novo synthesis: A crucial mechanism for hyperuricemia. FRONT NUTR. 2022 Dec 19;9:1045805Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded rat brain labeled with Anti-Glutamine PRPP amidotransferase Polyclonal Antibody, Unconjugated (bs-6359R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Formalin-fixed and paraffin embedded mouse placenta labeled with Anti-Glutamine PRPP amidotransferase Polyclonal Antibody, Unconjugated (bs-6359R) at 1:200 followed by conjugation to the secondary antibody and DAB staining