bs-6076R [Primary Antibody]
MTUS1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: MTUS1

Immunogen Range: 1151-1270/1270


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 57509

Swiss Prot: Q9ULD2

Source: KLH conjugated synthetic peptide derived from human MTUS1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 141


Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Human
Rat
Dog
Cow
Horse
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Chen ZZ et al. Tanshinone IIA contributes to the pathogenesis of endometriosis via renin angiotensin system by regulating the dorsal root ganglion axon sprouting. Life Sci. 2019 Nov 20;240:117085.Read more>>
  • Nikhil Ranjan. et al. The Tumor Suppressor MTUS1/ATIP1 Modulates Tumor Promotion in Glioma: Association with Epigenetics and DNA Repair. Cancers. 2021 Jan;13(6):1245Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded rat pancreas tissue labeled with Anti-MTUS1 Polyclonal Antibody, Unconjugated (bs-6076R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Formalin-fixed and paraffin embedded rat transplantation tumor tissue labeled with Anti-MTUS1 Polyclonal Antibody, Unconjugated (bs-6076R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Mouse uterus lysates probed with MTUS1 Polyclonal Antibody, unconjugated (bs-6076R) at 1:300 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.