DATASHEET
Formulation
Powder
Storage:
Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 614.2
Formula: C30 H40 Cl N7 O3 S
CAS Number: 761439-42-3
InChi Key: QQWUGDVOUVUTOY-UHFFFAOYSA-N
InChi: InChI=1S/C30H40ClN7O3S/c1-21(2)42(39,40)28-8-6-5-7-26(28)33-29-24(31)20-32-30(35-29)34-25-10-9-23(19-27(25)41-4)37-13-11-22(12-14-37)38-17-15-36(3)16-18-38/h5-10,19-22H,11-18H2,1-4H3,(H2,32,33,34,35)
Smiles: CN1CCN(CC1)C1CCN(CC1)C1=CC(OC)=C(C=C1)NC1N=C(NC2C=CC=CC=2S(=O)(=O)C(C)C)C(Cl)=CN=1
Purity: 98.0
Solubility: 10 mM in DMSO
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
NVP-TAE 684 is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM.