bs-60316C
[Life Science]
MSAB, β-catenin Inhibitor
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 305.35
Formula: C15 H15 N O4 S
CAS Number: 173436-66-3
InChi Key: CVKBYFCJQSPBOI-UHFFFAOYSA-N
InChi: InChI=1S/C15H15NO4S/c1-11-6-8-14(9-7-11)21(18,19)16-13-5-3-4-12(10-13)15(17)20-2/h3-10,16H,1-2H3
Smiles: CC1C=CC(=CC=1)S(=O)(=O)NC1C=C(C=CC=1)C(=O)OC
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C15 H15 N O4 S
CAS Number: 173436-66-3
InChi Key: CVKBYFCJQSPBOI-UHFFFAOYSA-N
InChi: InChI=1S/C15H15NO4S/c1-11-6-8-14(9-7-11)21(18,19)16-13-5-3-4-12(10-13)15(17)20-2/h3-10,16H,1-2H3
Smiles: CC1C=CC(=CC=1)S(=O)(=O)NC1C=C(C=CC=1)C(=O)OC
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
MSAB is a potent and selective Wnt/β-catenin inhibitor identified using cell-based chemical screening. It binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes. MSAB shows potent anti-tumor effects selectively on Wnt-dependent cancer cells in vitro and in mouse cancer models.
Size: 10mg solid, 2 mg solid10mg solid, 2 mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.