bs-60287C [Life Science]
DMOG, Prolyl 4-hydroxylase (P4H) Inhibitor
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[email protected]
800.501.7654 [DOMESTIC]
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DATASHEET

Formulation Powder

Storage: Store in dry, dark place at -20C for 1 year.

Product Information:

Molecular Weight: 175.14

Formula: C6 H9 N O5

CAS Number: 89464-63-1

InChi Key: BNJOZDZCRHCODO-UHFFFAOYSA-N

InChi: InChI=1S/C6H9NO5/c1-11-4(8)3-7-5(9)6(10)12-2/h3H2,1-2H3,(H,7,9)

Smiles: COC(=O)CNC(=O)C(=O)OC

Purity: 98.0

Solubility: DMSO up to 100 mM; Water up to 100 mM

Appearance: Solid Power.

Shelf Life: 1.0 years

Description:

DMOG is a selective, competitive and cell permeable prolyl 4-hydroxylase (P4H) inhibitor. It inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH). It acts to stabilize HIF-1α expression at normal oxygen tensions in cultured cells, at concentrations between 0.1 and 1 mM. DMOG acts as a pro-angiogenic compound, acting via the HIF-1α system.

Size: 2 mg solid,10 mg solid 2 mg solid,10 mg solid

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.