DATASHEET
Formulation
Powder
Storage:
Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 175.14
Formula: C6 H9 N O5
CAS Number: 89464-63-1
InChi Key: BNJOZDZCRHCODO-UHFFFAOYSA-N
InChi: InChI=1S/C6H9NO5/c1-11-4(8)3-7-5(9)6(10)12-2/h3H2,1-2H3,(H,7,9)
Smiles: COC(=O)CNC(=O)C(=O)OC
Purity: 98.0
Solubility: DMSO up to 100 mM; Water up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
DMOG is a selective, competitive and cell permeable prolyl 4-hydroxylase (P4H) inhibitor. It inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH). It acts to stabilize HIF-1α expression at normal oxygen tensions in cultured cells, at concentrations between 0.1 and 1 mM. DMOG acts as a pro-angiogenic compound, acting via the HIF-1α system.