DATASHEET
Formulation
Powder
Storage:
Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 319.38
Formula: C14 H17 N5 O2 S
CAS Number: 1426152-53-5
InChi Key: MYTRGTBDVGKKRO-UHFFFAOYSA-N
InChi: InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5,8H,1-3,6-7,9H2,(H2,15,16,21)
Smiles: O=C(CNC(=O)NC1=CC2SN=NC=2C=C1)N1CCCCC1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
UNC2327 is a potent and selective allosteric protein arginine methyltransferase 3 (PRMT3) inhibitor with IC50 ~ 230 nM. It occupies a novel allosteric binding site and is noncompetitive with both the peptide substrate and cofactor.