bs-60226C
[Life Science]
BAZ2-ICR --- BAZ2 Bromodomain Inhibitor
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 357.41
Formula: C20 H19 N7
CAS Number: 1665195-94-7
InChi Key: RRZVGDGTWNQAPW-UHFFFAOYSA-N
InChi: InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27)17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3
Smiles: CN1C=C(C=N1)C1N=CN(CCC2C=NN(C)C=2)C=1C1=CC=C(C=C1)C#N
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C20 H19 N7
CAS Number: 1665195-94-7
InChi Key: RRZVGDGTWNQAPW-UHFFFAOYSA-N
InChi: InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27)17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3
Smiles: CN1C=C(C=N1)C1N=CN(CCC2C=NN(C)C=2)C=1C1=CC=C(C=C1)C#N
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
BAZ2-ICR is a potent and selective BAZ2 bromodomain inhibitor with Kd values of 109 and 170 nM for BAZ2A and BAZ2B, respectively. It exhibits 15-fold selectivity for the BAZ2 bromodomain over the CERC2 bromodomain and >100-fold selectivity over a range of other bromodomains. It shows accelerated FRAP recovery at 1 ¦ÌM in the BAZ2A FRAP assay.
Size: 10mg solid, 2 mg solid10mg solid, 2 mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.