bs-60212C
[Life Science]
SCH51344, MTH1 Inhibitor
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 316.36
Formula: C16 H20 N4 O3
CAS Number: 171927-40-5
InChi Key: YWEGXZZAORIRQR-UHFFFAOYSA-N
InChi: InChI=1S/C16H20N4O3/c1-10-14-15(17-5-7-23-8-6-21)12-9-11(22-2)3-4-13(12)18-16(14)20-19-10/h3-4,9,21H,5-8H2,1-2H3,(H2,17,18,19,20)
Smiles: CC1=NNC2=NC3=CC=C(C=C3C(NCCOCCO)=C12)OC
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C16 H20 N4 O3
CAS Number: 171927-40-5
InChi Key: YWEGXZZAORIRQR-UHFFFAOYSA-N
InChi: InChI=1S/C16H20N4O3/c1-10-14-15(17-5-7-23-8-6-21)12-9-11(22-2)3-4-13(12)18-16(14)20-19-10/h3-4,9,21H,5-8H2,1-2H3,(H2,17,18,19,20)
Smiles: CC1=NNC2=NC3=CC=C(C=C3C(NCCOCCO)=C12)OC
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
SCH-51344 is an inhibitor of RAS/RAC-mediated cell morphology pathway. RAS interacts with multiple targets in the cell and controls at least two signaling pathways, one regulating extracellular signal-regulated kinase (ERK) activation and the other controlling membrane ruffling formation. SCH 51344 specifically blocks membrane ruffling induced by activated forms of H-RAS, K-RAS, N-RAS, and RAC. SCH 51344 was effective in inhibiting the anchorage-independent growth of Rat-2 fibroblast cells transformed by the three forms of oncogenic RAS and RAC V12.
Size: 10mg solid, 2 mg solid10mg solid, 2 mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.