bs-60197C
[Life Science]
TCID --- Ubiquitin C-terminal Hydrolase-L3 (UCH-L3) Inhibitor
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 283.92
Formula: C9 H2 Cl4 O2
CAS Number: 30675-13-9
InChi Key: IDLAOWFFKWRNHB-UHFFFAOYSA-N
InChi: InChI=1S/C9H2Cl4O2/c10-6-4-2(14)1-3(15)5(4)7(11)9(13)8(6)12/h1H2
Smiles: O=C1CC(=O)C2C1=C(Cl)C(Cl)=C(Cl)C=2Cl
Purity: 98.0
Solubility: DMSO up to 50 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C9 H2 Cl4 O2
CAS Number: 30675-13-9
InChi Key: IDLAOWFFKWRNHB-UHFFFAOYSA-N
InChi: InChI=1S/C9H2Cl4O2/c10-6-4-2(14)1-3(15)5(4)7(11)9(13)8(6)12/h1H2
Smiles: O=C1CC(=O)C2C1=C(Cl)C(Cl)=C(Cl)C=2Cl
Purity: 98.0
Solubility: DMSO up to 50 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
TCID is a novel potent and selective inhibitor of ubiquitin C-terminal hydrolase-L3 (UCH-L3) with an IC50 ~0.6 μM. It has ~125-fold greater selectivity over UCH-L1 (ubiquitin C-terminal hydrolase L1, IC50 ~75 μM). TCID can diminish glycine transporter GlyT2 ubiquitination in brain stem and spinal cord primary neurons.
Size: 2 mg solid, 10mg solid2 mg solid, 10mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.