DATASHEET
Formulation
Powder
Storage:
Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 225.29
Formula: C15 H15 N O
CAS Number: 1357302-64-7
InChi Key: DSOJSZXQRJGBCW-LSDHHAIUSA-N
InChi: InChI=1S/C15H15NO/c16-15-9-14(15)11-6-4-10(5-7-11)12-2-1-3-13(17)8-12/h1-8,14-15,17H,9,16H2/t14-,15+/m0/s1
Smiles: N[C@@H]1C[C@H]1C1C=CC(=CC=1)C1=CC(O)=CC=C1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
OG-L002 is a highly potent and specific inhibitor of Lysine Specific Demethylase-1 (LSD1). It inhibits LSD1 in biochemical assay with an IC50 ~20 nM, and has moderate inhibitory activity against monoamine oxidases MAO-A and MAO-B with IC50 ~1.38 µM and 0.72µM respectively. It potently repressed herpes simplex virus (HSV) IE gene expression, genome replication, and reactivation from latency. OG-L002 suppressed primary lytic infection of HSV in vivo in a mouse model.
Size:
10mg solid, 2 mg solid,10 mM in DMSO (0.888 10mg solid, 2 mg solid,10 mM in DMSO (0.888 mL)
Applications:
Life Science()
For research use only. Not intended for diagnostic or therapeutic use.