bs-60158C
[Life Science]
Daidzein-2c, Osteogenic Modulator
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 296.32
Formula: C18 H16 O4
CAS Number: 97846-18-9
InChi Key: DEQMUPGWSXUDKV-UHFFFAOYSA-N
InChi: InChI=1S/C18H16O4/c1-11(2)22-14-7-8-15-17(9-14)21-10-16(18(15)20)12-3-5-13(19)6-4-12/h3-11,19H,1-2H3
Smiles: CC(C)OC1C=C2OC=C(C(=O)C2=CC=1)C1C=CC(O)=CC=1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C18 H16 O4
CAS Number: 97846-18-9
InChi Key: DEQMUPGWSXUDKV-UHFFFAOYSA-N
InChi: InChI=1S/C18H16O4/c1-11(2)22-14-7-8-15-17(9-14)21-10-16(18(15)20)12-3-5-13(19)6-4-12/h3-11,19H,1-2H3
Smiles: CC(C)OC1C=C2OC=C(C(=O)C2=CC=1)C1C=CC(O)=CC=1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
Daidzein-2c is a potent synthetic daidzein analog, has osteogenic induction potentials on human Mesenchymal Stem Cells (MSC). Human bone marrow derived mesenchymal stem cells from three different donors were treated with Daidzein-2c and shown to exhibit enhanced osteogenesis when compared to daidzein or estrogen treatment. The enhanced osteogenic induction by Daidzein-2c resulted in increased osterix (Sp7), alkaline phosphatase (ALP), osteopontin (OPN), and insulin-like growth factor 1 (IGF-1), which are osteogenic factors that regulate the maturation of osteogenic progenitor cells into more differentiated osteoblast cells. It serves as a useful chemical tool to further validate and develop novel treatments of osteoporosis via promoting bone formation.
Size: 10 mg solid , 2mg solid ,10 mM in DMSO (0.6 10 mg solid , 2mg solid ,10 mM in DMSO (0.675 mL)
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.