bs-60026C
[Life Science]
PS48 --- PDK1 Activator
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 286.75
Formula: C17 H15 Cl O2
CAS Number: 1180676-32-7
InChi Key: LLJYFDRQFPQGNY-QINSGFPZSA-N
InChi: InChI=1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-
Smiles: OC(=O)C=C(CCC1C=CC(Cl)=CC=1)C1C=CC=CC=1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C17 H15 Cl O2
CAS Number: 1180676-32-7
InChi Key: LLJYFDRQFPQGNY-QINSGFPZSA-N
InChi: InChI=1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-
Smiles: OC(=O)C=C(CCC1C=CC(Cl)=CC=1)C1C=CC=CC=1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
PS48 is a novel PDK1 (phosphoinositide-dependent protein kinase 1) activator (Kd = 10.3 μM), which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 has been used to enhance iPSC reprogramming from human epidermal keratinocytes and endothelial cells.
Size: 5 mg solid,10 mM in DMSO (1.748 mL) 5 mg solid,10 mM in DMSO (1.748 mL)
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.