bs-60011C
[Life Science]
Y-27632 --- Rock Inhibitor.
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 247.34
Formula: C14 H21 N3 O
CAS Number: 146986-50-7
InChi Key: IYOZTVGMEWJPKR-IJLUTSLNSA-N
InChi: InChI=1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11-,12-/m1/s1
Smiles: C[C@@H](N)[C@@H]1CC[C@H](CC1)C(=O)NC1C=CN=CC=1
Purity: 98.0
Solubility: DMSO up to 100mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C14 H21 N3 O
CAS Number: 146986-50-7
InChi Key: IYOZTVGMEWJPKR-IJLUTSLNSA-N
InChi: InChI=1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11-,12-/m1/s1
Smiles: C[C@@H](N)[C@@H]1CC[C@H](CC1)C(=O)NC1C=CN=CC=1
Purity: 98.0
Solubility: DMSO up to 100mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
Y-27632 is a widely used, selective inhibitor of the Rho-associated protein kinase p160ROCK with a Ki value at ~ 0.14 μM. In many studies, it was shown and used to enhance the survival and cloning efficiency of many primary cell types after single cell dissociation without affecting their self-renewal properties, including hESC/iPSCs, neural stem cells, intestinal stem cells, and mammary epithelial cells.
Size: 10mg solid, 2mg solid , 10 mM in DMSO (0.81010mg solid, 2mg solid , 10 mM in DMSO (0.810 mL)
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.