bs-60009C
[Life Science]
Thiazovivin --- Rock Inhibitor
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 311.36
Formula: C15 H13 N5 O S
CAS Number: 1226056-71-8
InChi Key: DOBKQCZBPPCLEG-UHFFFAOYSA-N
InChi: InChI=1S/C15H13N5OS/c21-14(17-8-11-4-2-1-3-5-11)12-9-22-15(19-12)20-13-6-7-16-10-18-13/h1-7,9-10H,8H2,(H,17,21)(H,16,18,19,20)
Smiles: O=C(NCC1C=CC=CC=1)C1=CSC(NC2C=CN=CN=2)=N1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C15 H13 N5 O S
CAS Number: 1226056-71-8
InChi Key: DOBKQCZBPPCLEG-UHFFFAOYSA-N
InChi: InChI=1S/C15H13N5OS/c21-14(17-8-11-4-2-1-3-5-11)12-9-22-15(19-12)20-13-6-7-16-10-18-13/h1-7,9-10H,8H2,(H,17,21)(H,16,18,19,20)
Smiles: O=C(NCC1C=CC=CC=1)C1=CSC(NC2C=CN=CN=2)=N1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
Thiazovivin is a highly potent, selective, and cell-permeable small molecule Rock inhibitor with effective cellular activity ~ 2 μM. It can enhance survival of human embryonic stem cells (hESCs) or iPSCs after single cell dissociation by trypsin, and dramatically improve the reprogramming efficiency of iPSC (>200 folds) from human fibroblasts when used in combination with SB431542 and PD0325091. It has been shown to exhibit better activity than Y27632 in many stem cell assays.
Size: 2 mg solid, 25mg solid, 10 mM in DMSO (0.6432 mg solid, 25mg solid, 10 mM in DMSO (0.643 mL)
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.