bs-5449R-PE

DATASHEET

Host: Rabbit

Target Protein: IGF1R Tyr1165 + Tyr1166

Modification Site: Tyr1165 + Tyr1166

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3480

Swiss Prot: P08069

Source: KLH conjugated synthetic phosphopeptide derived from human IGF1R around the phosphorylation site of Tyr1165+Tyr1166

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008].

Conjugation: PE

Excitation/ Emission: 496,564nm/578nm

Size: 100ul

Concentration: 1ug/ul

Applications: FCM(1:20-100)

Predicted Molecular Weight: 150

Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Dog
Cow
Pig
Chicken

For research use only. Not intended for diagnostic or therapeutic use.