bs-5198R-BF405

DATASHEET

Host: Rabbit

Target Protein: ATG16 Ser287

Modification Site: Ser287

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 55054

Swiss Prot: Q676U5

Source: KLH conjugated Synthesised phosphopeptide derived from human ATG16A/ATG16L1 around the phosphorylation site of Ser287

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.

Conjugation: AbBy Fluor® 405

Excitation/ Emission: 401nm/421nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 68

Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Human
Rat
Cow
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.