bs-51112R

DATASHEET

Host: Rabbit

Target Protein: MeCP2

Clonality: Polyclonal

Isotype: Not determined

Entrez Gene: 4204

Swiss Prot: P51608

Source: Polyclonal antibody raised in rabbit against MeCP2 (Methyl-CpG-binding domain protein 2), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).

Size: 50ug

Concentration: 1.2ug/ul

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.