bs-51086R

DATASHEET

Host: Rabbit

Target Protein: CDYL

Clonality: Polyclonal

Isotype: Not determined

Entrez Gene: 9425

Swiss Prot: Q9Y232

Source: Polyclonal antibody raised in rabbit against human CDYL (chromodomain protein, Y-like) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein

Purification: Whole antiserum from rabbit containing 0.05% azide

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4.

Size: 100ul

Concentration: Not Determined

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.