bs-51019R

DATASHEET

Host: Mouse

Target Protein: H3K27me3

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 8350

Swiss Prot: P68431

Source: Monoclonal antibody raised in mouse against histone H3 trimethylated at lysine 27 (H3K27me3), using a KLH-conjugated synthetic peptide.

Purification: Protein A purified monoclonal antibody in PBS containing 0.05% azide.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Size: 50ug

Concentration: 1ug/ul

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.