bs-5096R [Primary Antibody]
OSMR Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: OSMR

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 157869

Source: KLH conjugated synthetic peptide derived from human Oncostatin-M receptor

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Guo, Sen, et al. "Oncostatin M Confers Neuroprotection against Ischemic Stroke." The Journal of Neuroscience 35.34 (2015): 12047-12062.Read more>>
VALIDATION IMAGES

Lane 1: Human 293T cell lysates; Lane 2: Human A375 cell lysates; Lane 3: Human Raji cell lysates; Lane 4: Human HeLa cell lysates; Lane 5: Human HT-1080 cell lysates probed with OSMR Polyclonal Antibody, Unconjugated (bs-5096R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.