bs-4943R-BF405 [Conjugated Primary Antibody]
MPO Polyclonal Antibody, AbBy Fluor® 405 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: MPO

Immunogen Range: 678-745/745


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4353

Swiss Prot: P05164

Source: KLH conjugated synthetic peptide derived from human MPO

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.

Conjugation: AbBy Fluor® 405

Excitation/ Emission: 401nm/421nm

Size: 100ul

Concentration: 1ug/ul

Applications: FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 84


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Pig
Horse
Rabbit
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Hu, Hai Xia, et al. "Anti-inflammatory effects of Gualou Guizhi decoction in transient focal cerebral ischemic brains. Corrigendum in/mmr/12/3/3998." Molecular medicine reports 12.1 (2015): 1321-1327.Read more>>
  • Zheng, Jian, et al. "Lithium posttreatment confers neuroprotection through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats." Journal of Neurosurgery (2016): 1-9.Read more>>
  • Thais Fantozzi,et al.Acute lung injury induced by intestinal ischemia and reperfusion is altered in obese female mice.(2018) Pulmonary Pharmacology & Therapeutics. 49:54-59.Read more>>
  • Sekerci,et al.Apelin/APJ expression in the heart and kidneys of hypertensive rats.(2018) Acta Histochemica. 120:196-204.Read more>>
  • Li Y et al. Role of intestinal microbiota-mediated genipin dialdehyde intermediate formation in geniposide-induced hepatotoxicity in rats. Toxicol Appl Pharmacol. 2019 Jun 11;377:114624. Read more>>
  • Emilia A Barbuet al. Detection and Quantification of Histone H4 Citrullination in Early NETosis With Image Flow Cytometry Version 4. Front Immunol. 2020 Jul 16;11:1335.Read more>>
  • oon Ching Teeet al. Xenogeneic mesenchymal stem cell transplantation for mandibular defect regeneration. Xenotransplantation. 2020 Sep;27(5):e12625.Read more>>
  • Tae-Young Kim. et al. Facilitation of Bone Healing Processes Based on the Developmental Function of Meox2 in Tooth Loss Lesion. Int J Mol Sci. 2020 Jan;21(22):8701Read more>>
  • Kyle Jablonski. et al. Physical activity prevents acute inflammation in a gout model by downregulation of TLR2 on circulating neutrophils as well as inhibition of serum CXCL1 and is associated with decreased pain and inflammation in gout patients. Plos One. 2020 Oct;15(10):e023752Read more>>
  • Chuntong Bao. et al. IFN--/- mice resist Actinobacillus pleuropneumoniae infection by promoting early lung IL-18 release and PMN-I accumulation. Infect Immun. 2021 Mar;:IAI.00069-21Read more>>
  • Yin Xian. et al. Sleeve Gastrectomy Attenuates the Severity of Cerulein-Induced Acute Pancreatitis in Obese Rats. 2021 Jun 21Read more>>
  • Ye, Buqing. et al. Induction of functional neutrophils from mouse fibroblasts by thymidine through enhancement of Tet3 activity. Cell Mol Immunol. 2022 Mar;:1-15Read more>>
  • Noive Arteche-Villasol. et al. Assessment of Paratuberculosis Vaccination Effect on In Vitro Formation of Neutrophil Extracellular Traps in a Sheep Model. VACCINES-BASEL. 2022 Sep;10(9):1403Read more>>
  • Uygar Sa??k. et al. Effect of ferulic acid on testicular damage caused by torsion-detorsion in rats. BIOTECH HISTOCHEM. 2022 Aug 23Read more>>
  • ae Ju-Eun. et al. Effects of erythropoietin on osteoblast in the tooth extraction socket in mice periodontitis model. FRONT PHYSIOL. 2022 Oct;0:2117Read more>>
  • Li Yue. et al. Effects of resveratrol and its derivative pterostilbene on hepatic injury and immunological stress of weaned piglets challenged with lipopolysaccharide. J ANIM SCI. 2022 OcRead more>>
  • Criado Miguel. et al. Evaluation of the innate immune response of caprine neutrophils against Mycobacterium avium subspecies paratuberculosis in vitro. VET RES. 2023 Dec;54(1):1-16Read more>>
  • Hao Gao. et al. Electroacupuncture treatment improves postoperative ileus by inhibiting the Th1 cell-mediated inflammatory response through the vagus nerve. ACUPUNCT MED. ;()Read more>>
  • Miguel Criado. et al. No Evidence of Neutrophil Response Modulation in Goats after Immunization against Paratuberculosis with a Heat-Inactivated Vaccine. ANIMALS. 2024 Jan;14(11):1694Read more>>
VALIDATION IMAGES