bs-49248P

DATASHEET

Entrez Gene: 6737

Swiss Prot: P19474

Source: Recombinant human TRIM21 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 195-475/475

Storage Buffer: 20mM Tris-HCl (pH8.0) with 8M Urea.

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008].

Sequence: 195-475/475

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 35.9

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.