DATASHEET
Host:
Rabbit
Target Protein:
MCSF
Immunogen Range:
201-300/554
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
1435
Swiss Prot:
P09603
Source:
KLH conjugated synthetic peptide derived from human MCSF
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
PRODUCT SPECIFIC PUBLICATIONS
- Vladimir Grubi?i?. et al. Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation. Cell Rep. 2020 Sep;32:1081Read more>>
- Shijie Fan. et al. Selenium maintains intestinal epithelial cells to activate M2 macrophages against deoxynivalenol injury. FREE RADICAL BIO MED. 2024 ApRead more>>
VALIDATION IMAGES
Mouse lung lysate probed with Rabbit Anti-MCSF Polyclonal Antibody (bs-4910R) at 1:300 overnight in 4˚C. Followed by conjugation to the secondary antibody (bs-0295G-HRP) at 1:5000 90min in RT
Formalin-fixed and paraffin embedded human spleen labeled with Rabbit Anti MCSF/M-CSF Polyclonal Antibody, Unconjugated (bs-4910R) at 1:200 followed by conjugation to the secondary antibody and DAB staining