bs-4858R-BF488

DATASHEET

Host: Rabbit

Target Protein: Hepatitis C Virus RNA-directed RNA polymerase

Immunogen Range: 2501-2600/3010

Clonality: Polyclonal

Isotype: IgG

Source: KLH conjugated synthetic peptide derived from Hepatitis C Virus RNA-directed RNA polymerase

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The RNA directed RNA polymerase is also known as non-structural protein NS5B. NS5B is a 65 kDa protein that resembles other viral RNA polymerases. Hepatitis C virus (HCV) replication is thought to occur in membrane bound replication complexes. These complexes transcribe the positive strand and the resulting minus strand is used as a template for the synthesis of genomic RNA. There are two viral proteins involved in the reaction, NS3 and NS5B

Conjugation: AbBy Fluor® 488

Excitation/ Emission: 499nm/519nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 65

Cross Reactive Species: Virus
(HCV)

For research use only. Not intended for diagnostic or therapeutic use.