DATASHEET
Host:
Rabbit
Target Protein:
TACI
Immunogen Range:
21-120/293
Clonality:
Polyclonal
Isotype:
IgG
Source:
KLH conjugated synthetic peptide derived from human TNFRSF13B/TACI
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17.
PRODUCT SPECIFIC PUBLICATIONS
- Sen Luo. et al. Three-gene signature revealing the dynamics of lymphocyte infiltration in subchondral bone during osteoarthritis progression. INT IMMUNOPHARMACOL. 2024 Aug;137:112431Read more>>
VALIDATION IMAGES
Mouse spleen lysates probed with TACI Polyclonal Antibody, Unconjugated (bs-4841R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: Mouse Stomach tissue lysates; Lane 2: Mouse Lung tissue lysates probed with TACI Polyclonal Antibody, Unconjugated (bs-4841R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.