bs-46110P [Protein]
Recombinant Human ACE2 Protein
www.biossusa.com
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DATASHEET

Entrez Gene: NP_001358344.1

Swiss Prot: Q9BYF1

Source: Recombinant Human ACE2 Protein protein is expressed in Mammalian cells with C-His. It contains the amino acid sequence of Met1-Ser740.

Storage Buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.

Storage: The product should be stored at -70°C or -20°C.

Background:

Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family. The ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be highly expressed in testis, kidney, and heart, in the colon, small intestine, and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor, don’t inhibit ACE-2 activity. ACE-2 may play an essential role in regulating heart function.

Endotoxin: Not Tested

Purity: >95% as determined by SDS-PAGE

Sequence: Met1-Ser740

Expression: Mammalian cells

Tag: C-His

Size: 100ug,500ug

Applications: WB()
ELISA()

Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Vincent Binette. et al. Corilagin and 1,3,6-Tri-O-galloy--D-glucose: potential inhibitors of SARS-CoV-2 variants. Phys Chem Chem Phys. 2021 Jul;23(27):14873-14888Read more>>